Advanced Keratoprosthesis & Ocular Surface Reconstruction

Osteo-Odonto-Keratoprosthesis (OOKP)

A highly specialized staged reconstructive procedure using an autologous tooth-bone lamina to support an optical cylinder in selected end-stage ocular surface disease.

Osteo-Odonto-Keratoprosthesis (OOKP)
Clinical overview

Indications, strategy and clinical context

OOKP is one of the most complex and remarkable reconstructive procedures in ophthalmology. It is designed for end-stage ocular surface disease, especially in severely dry, keratinized or cicatrizing eyes in which a conventional corneal graft or even a standard Type I keratoprosthesis is unlikely to survive.

The technique uses an autologous tooth-bone lamina to support the optical cylinder and is usually combined with mucosal surface reconstruction, creating a biological environment capable of protecting the device in the most hostile ocular surfaces.

Indications
End-stage dry ocular surface diseaseSevere chemical burns, cicatrizing disease, keratinization and advanced surface failure where more conventional options are not appropriate.
Concept
Biological support for an optical cylinderThe osteo-dental lamina acts as a living autologous support, making OOKP fundamentally different from Boston Type I keratoprosthesis.
Selection
A surgery for very specific eyesPatient selection, systemic history and visual potential assessment are essential before indicating OOKP.
Medical information reviewed for this website on 24 August 2026. Final treatment selection requires an individualized ophthalmic assessment.
Evidence & innovation

Selected scientific evidence.

Each surgical strategy is linked to peer-reviewed publications and long-term clinical experience. Select an article below to open its PubMed record.

Appointments · Barcelona & Online

Request an evaluation.

Patients and referring ophthalmologists can request an in-person consultation in Barcelona or an online preliminary evaluation of the case. Clinical reports, slit-lamp photographs, imaging and previous surgical history can be reviewed before travel.

International Department
[email protected]
Oftalvist Barcelona
C/ Anglí, 40
08017 Barcelona · Spain
HLA Internacional Barcelona · 4th floor
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